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Over-the-counter cold medicines, cough syrups, diet pills, or some different containing drugs which increase the creation of norepinephrine make IC worse. The British government was alarmed by these findings who's decided in 2003 to warn doctors to never prescribe SSRIs to anyone under 18 years. IC patients will rarely test positive for infection each time a urinalysis and urine cultures are tested. Any of those signs indicates decreased tear production. There isn't any primary immune-inflammatory attack about the eye surface in dry eye.

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