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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight loss in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it you should err along the side of caution and allow the FDA do its job and demand some investigation be done in order that the public knows the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications.

Researchers found out that participants using this drug for the year, dropped a few pounds within one month and have kept the body weight off through the 56 weeks from the study. Contrave is really a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, that might make them more potent and safer.

Combo-pilling could be the newest fad or even better the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that by right now there are no long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations happen to be rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug may also raise blood pressure level and heart rate, and shouldn't be used in individuals with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high blood pressure level, along with by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.


A pyromaniac, with both psychiatric and medical therapy, can still be treated. It is best done with behavioral therapy. Psychotherapy treatment alongside behavior modification is the most frequently used treatment. Based on the study of Jon Grant, a combination treatment of drugs and behavioral therapy was found to be successful for treating pyromania. The usage of serotonin reuptake inhibitors can be beneficial in managing the impulsive behavior of the patient such as other impulse control disorder. Also of great help for the patient are medications including Lithium, naltrexone, (ReVia), fluoxetine (Prozac), citalopram (Celexa), paroxetene (Paxil), along with other antidepressants.